Adrenocorticotropic Hormone (ACTH) Effects on Myelination in Subjects With MS

Summary

The primary objective of this study is to determine if monthly pulse doses of a three-day course ACTH (H.P. Acthar®) is more effective at recovering myelin at 12 months, as measured by myelin water fraction (MWF), in new multiple sclerosis lesions as compared to one course of treatment. The main secondary objective is to utilize every three month MWF measurements to determine the peak time of remyelination in new multiple sclerosis lesions when followed over the course of 12 months.

Timeline

Start

2016-06

Primary completion

2020-03

Completion

2020-06

Drugs

Indications