The Effect of the Serratus Block on Pain Control After Breast Surgery

Phase 2/3 Completed 40 enrolled Women's College Hospital

RandomizedParallel-groupQuadruple-blindTreatment

Summary

Surgery for breast cancer is associated with significant pain. The serratus nerve block targets the interfascial plane either below or above the serratus muscle, blocking thereby the lateral cutaneous branches of the intercostal nerves. The purpose of this randomized controlled double-blinded study is to see whether the addition of a serratus nerve block to a general anesthesia results in a better postoperative pain control in patients undergoing surgery for breast cancer.

Timeline

Start: 2014-10-29
Primary completion: 2019-09-11
Completion: 2019-12-11

Outcome

Missed primary endpoint

paper There were no differences in the quality of recovery-15 scores between patients in the serratus and control groups PMID 33492696 ↗

Publications

Abdallah FW, Patel V, Madjdpour C, Cil T, Brull R. Quality of recovery scores in deep serratus anterior plane block vs. sham block in ambulatory breast cancer surgery: a randomised controlled trial. Anaesthesia. 2021 Sep;76(9):1190-1197. doi: 10.1111/anae.15373. Epub 2021 Jan 25.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Epinephrine	Other / unclassified	—	Other
Subject	Ropivacaine	Other / unclassified	0.4 unknown	Other

Indications

No indication recorded.