drugset / Trial / NCT02460354

Metformin and Congenital Nephrogenic Diabetes Insipidus

NCT02460354 ↗

Phase 1 Terminated 2 enrolled Emory University
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to determine whether metformin can increase urine concentration (osmolality) and decrease the amount of urine in patients with congenital nephrogenic diabetes insipidus (NDI).

Timeline

Start
2015-09
Primary completion
2017-06
Completion
2017-06

Outcome

Outcome not reported

Stopped: “Lack of effect in initial subjects”

Drugs

EvaluationDrugModalityDoseRoute
Subject Metformin Small molecule 500 mg Oral