drugset / Trial / NCT02466074

Augmenting Cerebral Blood Flow to Treat Established Multiple Sclerosis

NCT02466074

RandomizedParallel-groupTriple-blindTreatment

Summary

This study will evaluate how improved cerebral blood flow affects the way in which newly formed MS lesions evolve and whether tissue repair is improved. Patients with multiple sclerosis (MS) will be treated with acetazolamide in daily divided doses and obtain MRI to determine how much and in which regions of the brain cerebral perfusion improves as well as the extent to which tissue integrity is improved in these areas.

Timeline

Start
2016-08-17
Primary completion
2022-02-07
Completion
2022-02-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Acetazolamide Small molecule Oral

Indications