drugset / Trial / NCT02466984
Subcutaneous Route and Pharmacology of Metoclopramide
RandomizedCrossoverOpen-labelTreatment
Summary
Subcutaneous (SC) route has become a standard of care of many drugs administration in palliative medicine. A preliminary study showed that, although it was widely adopted among palliative care practitioners for routinely prescribed medications, standards of proof are still lacking for many molecules. Among them, metoclopramide is a largely employed drug for nausea and vomiting treatment, particularly in palliative care and oncology. Therefore, the investigator aim to study absorption and efficacy of subcutaneous administration of metoclopramide.
Timeline
- Start
- 2016-07
- Primary completion
- 2018-02-08
- Completion
- 2019-02-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Metoclopramide | Small molecule | 10 mg | Subcutaneous |
| Subject | Metoclopramide | Small molecule | 20 mg | Subcutaneous |
| Subject | Metoclopramide | Small molecule | 30 mg | Subcutaneous |
Indications
No indication recorded.