drugset / Trial / NCT02475070
Vildagliptin Versus Dapagliflozin on Glucagon
RandomizedCrossoverOpen-labelBasic science
Summary
The aim of the study is to assess if vildagliptin and dapagliflozin have dissociated effects on glucagon secretion after a mixed meal ingestion in metformin-treated subjects with type 2 diabetes and whether this is associated with effects on glucose homeostasis.
Timeline
- Start
- 2016-01
- Primary completion
- 2017-06
- Completion
- 2017-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dapagliflozin | Small molecule | 10 mg | — |
| Comparator | Vildagliptin | Other / unclassified | 50 mg | — |