drugset / Trial / NCT02487225
Pentoxifylline Treatment in Acute Pancreatitis (AP)
Phase 3
Completed
83 enrolled
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of this study was to determine the effects (good and bad) of giving a drug called pentoxifylline to patients with acute pancreatitis.
Timeline
- Start
- 2015-05
- Primary completion
- 2017-04-30
- Completion
- 2017-10-31
Outcome
Missed primary endpoint
registry analysis (superiority test); Pentoxifylline vs Placebo; p = 0.5796; Kruskal-Wallis NCT02487225 ↗
registry analysis (superiority test); Pentoxifylline vs Placebo; p = 0.1109; Kruskal-Wallis NCT02487225 ↗
registry analysis (superiority test); Pentoxifylline vs Placebo; p = 0.1236; Kruskal-Wallis NCT02487225 ↗
registry analysis (superiority test); Pentoxifylline vs Placebo; p = 0.157; Kruskal-Wallis NCT02487225 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Pentoxifylline | Small molecule | 400 mg | Oral |