drugset / Trial / NCT02487485

Examining the Impact of Sirolimus on Ketamine's Antidepressant Effects

NCT02487485 ↗

Phase 2 Completed 23 enrolled Yale University
RandomizedCrossoverTriple-blindOther

Summary

The aim of the study is to provide insight into the impact of the immunosuppressant drug sirolimus, on the antidepressant effects of the prototypal rapid-acting antidepressant medication, ketamine.

Timeline

Start
2016-03
Primary completion
2020-01
Completion
2020-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Ketamine Small molecule 0.5 mg/kg Intravenous
Subject Sirolimus Small molecule 6 mg Oral

Indications