drugset / Trial / NCT02496780
The Impact of Insulin Therapy on Protein Turnover in Pre-Diabetic Cystic Fibrosis Patients
RandomizedParallel-groupTriple-blindTreatment
Summary
Insulin replacement therapy may be effective in breaking the cycle of protein catabolism, undernutrition and overall clinical deterioration in pre-diabetic, insulin insufficient CF youth because of its potent anabolic effect. A significant number of CF patients might benefit from this therapeutic approach with a substantial impact on morbidity and mortality.
Timeline
- Start
- 2015-08
- Primary completion
- 2022-07
- Completion
- 2022-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | insulin aspart | Protein / enzyme biologic | — | — |
| Subject | insulin detemir | Protein / enzyme biologic | — | — |