drugset

drugset / Trial / NCT02499029

N-acetylcysteine in the Treatment of PTSD and Addiction

NCT02499029 ↗

Phase 2 Completed 35 enrolled Medical University of South Carolina

RandomizedFactorialQuadruple-blindTreatment

Summary

Examine the effects of N-acetylcysteine on PTSD symptoms, craving and substance use in veterans with PTSD and comorbid substance use disorders.

Timeline

Start: 2013-02
Primary completion: 2014-09
Completion: 2014-09

Publications

Results Back SE, McCauley JL, Korte KJ, Gros DF, Leavitt V, Gray KM, Hamner MB, DeSantis SM, Malcolm R, Brady KT, Kalivas PW. A Double-Blind, Randomized, Controlled Pilot Trial of N-Acetylcysteine in Veterans With Posttraumatic Stress Disorder and Substance Use Disorders. J Clin Psychiatry. 2016 Nov;77(11):e1439-e1446. doi: 10.4088/JCP.15m10239.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	N-acetylcysteine	Small molecule	1200 mg	—

Indications