drugset / Trial / NCT02499627

Bendamustine Plus Brentuximab Vedotin in HL and CD30+ PTCL in First Salvage Setting

NCT02499627

Phase 2 Terminated 43 enrolled Fondazione Italiana Linfomi - ETS
NaSingle-groupOpen-labelTreatment

Summary

This is a single-arm, open-label, multicenter, phase 2 clinical trial aimed at evaluating the efficacy and safety of the combination of bendamustine and brentuximab vedotin as a first salvage therapy in patients with relapsed or refractory Hodgkin's lymphoma or PTCL. A total of 25 patients with PTCL, and 40 with Hodgkin's lymphoma are expected to be treated according to this treatment protocol.

Timeline

Start
2015-12-23
Primary completion
2019-09-13
Completion
2020-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Bendamustine Small molecule 90 mg/m2 Intravenous
Subject Brentuximab Vedotin Monoclonal antibody 1.8 mg/kg Intravenous