drugset / Trial / NCT02514031

ARQ-761 Treatment With Gemcitabine/Nab-Paclitaxel Chemotherapy In Pancreatic Cancer

NCT02514031

Phase 1 Terminated 17 enrolled University of Texas Southwestern Medical Center
NaSingle-groupOpen-labelOther

Summary

This is a study of ARQ-761 (beta-lapachone) with gemcitabine/nab-paclitaxel chemotherapy in subjects with advanced (metastatic, unresectable, or recurrent) pancreatic cancer that has not been treated with gemcitabine.

Timeline

Start
2016-03-24
Primary completion
2018-05-22
Completion
2022-05

Drugs

EvaluationDrugModalityDoseRoute
Subject ARQ761 Small molecule 195 mg Intravenous
Subject ARQ761 Small molecule 290 mg Intravenous
Subject ARQ761 Small molecule 390 mg Intravenous
Background Gemcitabine Small molecule 1000 mg/m2 Intravenous
Background Paclitaxel Small molecule 125 mg/m2 Intravenous