Comparative Bioavailability Study of Two Misoprostol Formulations

Phase 1 Completed 72 enrolled Region Skane

RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to compare pharmacokinetics of two formulations of misoprostol following single dose administration in adult women being given misoprostol for cervical ripening and induction of labour.

Timeline

Start: 2014-11
Primary completion: 2015-11
Completion: 2016-02

Publications

Amini M, Reis M, Wide-Swensson D. A Relative Bioavailability Study of Two Misoprostol Formulations Following a Single Oral or Sublingual Administration. Front Pharmacol. 2020 Feb 12;11:50. doi: 10.3389/fphar.2020.00050. eCollection 2020.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Misoprostol	Other / unclassified	25 ug	Oral
Comparator	Misoprostol	Other / unclassified	50 ug	Oral

Indications

No indication recorded.