drugset / Trial / NCT02518594
A Trial of Pessary and Progesterone for Preterm Prevention in Twin Gestation With a Short Cervix
Phase 3
Completed
1311 enrolled
The George Washington University Biostatistics Center
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · collab
RandomizedParallel-groupQuadruple-blindPrevention
Summary
This protocol outlines a randomized trial of 630 women evaluating the use of micronized vaginal progesterone or pessary versus control (placebo) to prevent early preterm birth in women carrying twins and with a cervical length of less than 30 millimeters.
Timeline
- Start
- 2015-11-13
- Primary completion
- 2024-12-15
- Completion
- 2025-02-18
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Progesterone | Other / unclassified | 200 mg | Other |