drugset / Trial / NCT02526303
Anticoagulation for Non-occlusive Portal Vein Thrombosis in Patients With Liver Cirrhosis
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to determine the safety and efficacy of anticoagulation in the treatment of non-occlusive portal vein thrombosis in patients with liver cirrhosis.
Timeline
- Start
- —
- Primary completion
- 2017-02
- Completion
- —
Publications
- Background Qi X, Han G, Fan D. Management of portal vein thrombosis in liver cirrhosis. Nat Rev Gastroenterol Hepatol. 2014 Jul;11(7):435-46. doi: 10.1038/nrgastro.2014.36. Epub 2014 Apr 1.
- Background Nery F, Chevret S, Condat B, de Raucourt E, Boudaoud L, Rautou PE, Plessier A, Roulot D, Chaffaut C, Bourcier V, Trinchet JC, Valla DC; Groupe d'Etude et de Traitement du Carcinome Hepatocellulaire. Causes and consequences of portal vein thrombosis in 1,243 patients with cirrhosis: results of a longitudinal study. Hepatology. 2015 Feb;61(2):660-7. doi: 10.1002/hep.27546. Epub 2015 Jan 5.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Nadroparin Calcium | Other / unclassified | 85 iu/kg | Subcutaneous |
| Subject | Warfarin | Small molecule | 2.5 mg | — |