drugset / Trial / NCT02527005
A Comparative Study of Azithromycin and S-P as Prophylaxis in Pregnant HIV+ Patients
RandomizedParallel-groupSingle-blindPrevention
Summary
Randomized controlled single blind prospective comparative study
Timeline
- Start
- 2015-09
- Primary completion
- 2016-08
- Completion
- 2016-08
Publications
- Background Taylor WR, Richie TL, Fryauff DJ, Picarima H, Ohrt C, Tang D, Braitman D, Murphy GS, Widjaja H, Tjitra E, Ganjar A, Jones TR, Basri H, Berman J. Malaria prophylaxis using azithromycin: a double-blind, placebo-controlled trial in Irian Jaya, Indonesia. Clin Infect Dis. 1999 Jan;28(1):74-81. doi: 10.1086/515071.
- Pons-Duran C, Wassenaar MJ, Yovo KE, Marin-Carballo C, Briand V, Gonzalez R. Intermittent preventive treatment regimens for malaria in HIV-positive pregnant women. Cochrane Database Syst Rev. 2024 Sep 26;9(9):CD006689. doi: 10.1002/14651858.CD006689.pub3.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Azithromycin | Small molecule | 500 mg | — |
| Comparator | pyrimethamine | Small molecule | 25 mg | — |
| Comparator | sulfadoxine | Small molecule | 500 mg | — |