drugset / Trial / NCT02531906

Gabapentin, Methadone Hydrochloride, and Oxycodone Hydrochloride in Improving Quality of Life in Patients With Stage II-IV Head and Neck Cancer During Chemoradiation

NCT02531906

Phase 1 Completed 60 enrolled Roswell Park Cancer Institute
RandomizedParallel-groupOpen-labelSupportive care

Summary

This randomized pilot clinical trial studies the side effects of gabapentin and how well it works when given together with methadone hydrochloride and oxycodone hydrochloride in improving quality of life in patients with stage II-IV head and neck cancer during chemoradiation. Gabapentin, methadone hydrochloride, and oxycodone hydrochloride may help relieve moderate or severe pain caused by head and neck cancer during and after chemoradiation therapy.

Timeline

Start
2015-04-24
Primary completion
2018-06-14
Completion
2018-06-14

Drugs

EvaluationDrugModalityDoseRoute
Subject Gabapentin Small molecule Oral
Subject Methadone Other / unclassified Oral
Subject Oxycodone Other / unclassified Oral