The Effects of Metformin in Patients With Mild Graves' Ophthalmopathy

Summary

This is a prospective, randomized, double-blind, placebo-controlled study about the effect of metformin in patients with mild Graves' ophthalmopathy. Eighty patients with mild ophthalmopathy will be included. Each patient will be given either metformin (500mg PO three times a day) or placebo ( PO three times a day ) for 6 months and then followed for 6 months after withdrawal of treatment.

Timeline

Start

2014-12

Primary completion

2019-10

Completion

2019-10

Drugs

Indications