drugset / Trial / NCT02541071

Influence of the Noradrenergic System on the Formation of Intrusive Memories

NCT02541071

Completed 118 enrolled Charite University, Berlin, Germany
RandomizedParallel-groupDouble-blindBasic science

Summary

Intrusive memories of traumatic events are core features of posttraumatic stress disorder (PTSD) but little is known about the neurobiological formation of intrusions. The aim of this study was to determine whether the activity of the noradrenergic system during an intrusion-inducing stressor influences subsequent intrusive memories.

Timeline

Start
2013-11
Primary completion
2014-10
Completion
2014-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Clonidine Other / unclassified 0.15 mg
Subject Yohimbine Small molecule 10 mg

Indications

No indication recorded.