drugset / Trial / NCT02543645

A Study of Varlilumab and Atezolizumab in Patients With Advanced Cancer

NCT02543645

Phase 1 Terminated 18 enrolled Celldex Therapeutics Genentech, Inc. · collab
NaSingle-groupOpen-labelTreatment

Summary

This is a study to determine the clinical benefit (how well the drug works), safety and tolerability of combining varlilumab and atezolizumab. Phase l of the study will enroll patients with a number of tumor types; Phase ll will enroll only patients with renal cell carcinoma (RCC).\* \*Note: This Study was terminated prior to initiation of Phase II

Timeline

Start
2015-10
Primary completion
2017-04
Completion
2017-05-22

Drugs

EvaluationDrugModalityDoseRoute
Subject Atezolizumab Monoclonal antibody 1200 mg
Subject Varlilumab Monoclonal antibody 0.3 mg/kg
Subject Varlilumab Monoclonal antibody 1 mg/kg
Subject Varlilumab Monoclonal antibody 3 mg/kg