Comparison of Carvedilol and Atenolol on Anti-anginal and Metabolic Effects in Patients With Stable Angina Pectoris

Phase 4 Completed 99 enrolled Gachon University Gil Medical Center

RandomizedParallel-groupOpen-labelTreatment

Summary

There are few data regarding anti-anginal effects between beta-blockers with and without vasodilating property. Beta-blocker without vasodilating property is generally known to have unfavorable effects on glucose and lipid metabolism. Therefore, the investigators compared carvedilol and atenolol on anti-anginal and metabolic effects in patient with stable angina pectoris.

Timeline

Start: 2011-04
Primary completion: 2013-08
Completion: 2013-08

Publications

Oh PC, Kang WC, Moon J, Park YM, Kim S, Kim MG, Lee K, Ahn T, Shin EK. Anti-Anginal and Metabolic Effects of Carvedilol and Atenolol in Patients with Stable Angina Pectoris: A Prospective, Randomized, Parallel, Open-Label Study. Am J Cardiovasc Drugs. 2016 Jun;16(3):221-8. doi: 10.1007/s40256-016-0168-1.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Atenolol	Other / unclassified	50 mg	—
Subject	Carvedilol	Other / unclassified	25 mg	—

Indications

No indication recorded.