Quality of Analgesia After Interscalene Block After Arthroscopic Shoulder Surgery

Completed 50 enrolled North American Institute for Continuing Medical Education (NAICE) New York School of Regional Anesthesia · collab Pacira Pharmaceuticals, Inc · collab

RandomizedParallel-groupDouble-blindTreatment

Summary

Shoulder arthroscopic causes post operative pain that outlasts analgesia provided by single injection nerve blocks.

Timeline

Start: 2015-07
Primary completion: 2016-01
Completion: 2016-03

Outcome

Met primary endpoint

paper Worst pain was lower in patients given liposome bupivacaine added to standard bupivacaine than in patients given standard bupivacaine alone PMID 28157791 ↗

Publications

Vandepitte C, Kuroda M, Witvrouw R, Anne L, Bellemans J, Corten K, Vanelderen P, Mesotten D, Leunen I, Heylen M, Van Boxstael S, Golebiewski M, Van de Velde M, Knezevic NN, Hadzic A. Addition of Liposome Bupivacaine to Bupivacaine HCl Versus Bupivacaine HCl Alone for Interscalene Brachial Plexus Block in Patients Having Major Shoulder Surgery. Reg Anesth Pain Med. 2017 May/Jun;42(3):334-341. doi: 10.1097/AAP.0000000000000560.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Bupivacaine	Other / unclassified	0.25 %	Other
Subject	Bupivacaine	Other / unclassified	5 ml	Other
Subject	Bupivacaine	Other / unclassified	10 ml	Other
Subject	Bupivacaine	Other / unclassified	15 ml	Other
Subject	Bupivacaine	Other / unclassified	133 mg	Other

Indications

No indication recorded.