drugset / Trial / NCT02571426

Renal Function During Pediatric Anesthesia

NCT02571426

Phase 1 Completed 24 enrolled Uppsala University
RandomizedParallel-groupOpen-labelBasic science

Summary

It is known that volatile anesthesia, such as sevoflurane, retain water and that this appears more pronounced in children. However, the mechanisms for this effect is unknown and it is not clear if the commonly used anesthetic propofol does the same. In this study the investigators want to compare the fluid and electrolyte conserving effects of sevoflurane and propofol in a pediatric setting and also investigate humoral changes induced by these anesthetics.

Timeline

Start
2015-10
Primary completion
2018-03
Completion
2019-04

Drugs

EvaluationDrugModalityDoseRoute
Comparator Propofol Small molecule
Comparator Sevoflurane Other / unclassified

Indications