drugset / Trial / NCT02571426
Renal Function During Pediatric Anesthesia
RandomizedParallel-groupOpen-labelBasic science
Summary
It is known that volatile anesthesia, such as sevoflurane, retain water and that this appears more pronounced in children. However, the mechanisms for this effect is unknown and it is not clear if the commonly used anesthetic propofol does the same. In this study the investigators want to compare the fluid and electrolyte conserving effects of sevoflurane and propofol in a pediatric setting and also investigate humoral changes induced by these anesthetics.
Timeline
- Start
- 2015-10
- Primary completion
- 2018-03
- Completion
- 2019-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Propofol | Small molecule | — | — |
| Comparator | Sevoflurane | Other / unclassified | — | — |