drugset / Trial / NCT02576366
Phenotypic Drug Probes as Predictors of Drug-drug Interactions With Tacrolimus
Non-randomizedCrossoverOpen-labelDiagnostic
Summary
Single center, open label crossover study with 2 treatment phases in healthy volunteers. The potential of phenotypic drug probes to predict drug-drug interactions between tacrolimus, voriconazole and rifampin will be assessed.
Timeline
- Start
- 2016-06
- Primary completion
- 2017-05
- Completion
- 2017-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Rifampin | Small molecule | 600 mg | Oral |
| Subject | Voriconazole | Small molecule | 200 mg | Oral |
Indications
No indication recorded.