drugset / Trial / NCT02584725
Tranexamic Acid Dosing for Total Joint Arthroplasty
RandomizedParallel-groupTriple-blindTreatment
Summary
The purpose of this study is to determine the effect of increasing doses of tranexamic acid (TXA) on limiting blood loss during total knee and total hip arthroplasty as defined by a change in hemoglobin from pre-operative baseline to the first post-operative day.
Timeline
- Start
- 2014-12
- Primary completion
- 2015-06
- Completion
- 2015-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Tranexamic Acid | Small molecule | 5 mg/kg | Intravenous |
| Comparator | Tranexamic Acid | Small molecule | 10 mg/kg | Intravenous |
| Comparator | Tranexamic Acid | Small molecule | 15 mg/kg | Intravenous |