drugset / Trial / NCT02587572
Safety and Efficacy Trial Using Allogeneic Human Mesenchymal Stem Cells: The SIRONA Trial
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This is a phase 2b, randomized, placebo-controlled clinical trial designed to evaluate the safety and efficacy of Longeveron Mesenchymal Stem Cells (LMSCs) in subjects with metabolic syndrome and to assess the effects of LMSCs on endothelial function using several different doses.
Timeline
- Start
- 2023-12-01
- Primary completion
- 2023-12
- Completion
- 2023-12
Outcome
Outcome not reported
Stopped: “Sponsor has made decision not to conduct this clinical trial.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Mesenchymal stem cell | Cell therapy | 10 cells | Intravenous |
| Subject | Mesenchymal stem cell | Cell therapy | 20 cells | Intravenous |
| Subject | Mesenchymal stem cell | Cell therapy | 100 cells | Intravenous |