drugset / Trial / NCT02587845
Use of Transexamic Acid in Hip Replacement
RandomizedParallel-groupOpen-labelBasic science
Summary
Studies have shown that tranexamic acid reduces blood loss and transfusion need in patients undergoing total hip arthroplasty. However, no to date, no study has been large enough to determine definitively whether the drug is safe and effective. The present study was designed to verify noninferior efficacy and safety of topical intra-articular TXA compared with intravenous TXA in primary THA.
Timeline
- Start
- 2015-10
- Primary completion
- 2016-12
- Completion
- 2016-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Tranexamic Acid | Small molecule | 10 mg/kg | Intravenous |
| Comparator | Tranexamic Acid | Small molecule | 2 g | Intravenous |