drugset / Trial / NCT02587845

Use of Transexamic Acid in Hip Replacement

NCT02587845

Phase 3 Unknown 150 enrolled Samsung Medical Center
RandomizedParallel-groupOpen-labelBasic science

Summary

Studies have shown that tranexamic acid reduces blood loss and transfusion need in patients undergoing total hip arthroplasty. However, no to date, no study has been large enough to determine definitively whether the drug is safe and effective. The present study was designed to verify noninferior efficacy and safety of topical intra-articular TXA compared with intravenous TXA in primary THA.

Timeline

Start
2015-10
Primary completion
2016-12
Completion
2016-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Tranexamic Acid Small molecule 10 mg/kg Intravenous
Comparator Tranexamic Acid Small molecule 2 g Intravenous

Indications