drugset / Trial / NCT02588235

Ezetimibe and Atorvastatin Therapy on TCFA

NCT02588235

Phase 4 Unknown 100 enrolled Xijing Hospital
RandomizedParallel-groupOpen-labelPrevention

Summary

After successful coronary angiography and OCT examination, patients with TCFAs in non-culprit, mild-to-moderate stenotic lesions will be enrolled. Then, they will be randomly assigned in a 1:1 ratio to receive either atorvastatin (20 mg/day) alone or atorvastatin (20 mg/day)plus ezetimibe(10 mg/day)by envelope method. Angiographic and OCT follow-up will be scheduled for the target vessel after 12 months.

Timeline

Start
2015-10
Primary completion
2017-11
Completion
2017-11

Drugs

EvaluationDrugModalityDoseRoute
Comparator Atorvastatin Small molecule 20 mg
Subject Ezetimibe Unknown 10 mg