drugset / Trial / NCT02588235
Ezetimibe and Atorvastatin Therapy on TCFA
RandomizedParallel-groupOpen-labelPrevention
Summary
After successful coronary angiography and OCT examination, patients with TCFAs in non-culprit, mild-to-moderate stenotic lesions will be enrolled. Then, they will be randomly assigned in a 1:1 ratio to receive either atorvastatin (20 mg/day) alone or atorvastatin (20 mg/day)plus ezetimibe(10 mg/day)by envelope method. Angiographic and OCT follow-up will be scheduled for the target vessel after 12 months.
Timeline
- Start
- 2015-10
- Primary completion
- 2017-11
- Completion
- 2017-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Atorvastatin | Small molecule | 20 mg | — |
| Subject | Ezetimibe | Unknown | 10 mg | — |