drugset / Trial / NCT02597400

Drug-Drug Interaction Study of Glucokinase Activator HMS5552 and Metformin in T2DM

NCT02597400

Phase 1 Completed 12 enrolled Hua Medicine Limited
NaSingle-groupOpen-labelTreatment

Summary

This is a Phase 1, open-label, sequential, multiple-dose, drug-drug interaction study of GK activator HMS5552 and metformin in patients with type 2 diabetes mellitus (T2DM).

Timeline

Start
2015-10
Primary completion
2015-10
Completion
2015-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Dorzagliatin Small molecule 50 mg
Subject Metformin Small molecule 500 mg