drugset / Trial / NCT02597907
Postoperative Nausea and Vomiting: Ramosetron Plus Aprepitant vs Palonosetron Plus Aprepitant
RandomizedParallel-groupQuadruple-blindPrevention
Summary
The purpose of this study was to compare the antiemetic efficacy of aprepitant plus palonosetron versus aprepitant plus ramosetron in high risk patients undergoing laparoscopic cholecystectomy.
Timeline
- Start
- 2014-07
- Primary completion
- 2015-05
- Completion
- 2015-07
Outcome
Met primary endpoint
registry COUNT_OF_PARTICIPANTS Aprepitant Plus Palonosetron: 5 Participants NCT02597907 ↗
registry COUNT_OF_PARTICIPANTS Aprepitant Plus Ramosetron: 18 Participants NCT02597907 ↗
registry analysis (other test); Aprepitant Plus Palonosetron vs Aprepitant Plus Ramosetron; p <0.05; Fisher Exact NCT02597907 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Palonosetron | Other / unclassified | 0.075 mg | — |
| Comparator | Ramosetron | Small molecule | 0.3 mg | — |
| Background | Aprepitant | Other / unclassified | 80 mg | — |
Indications
No indication recorded.