Effect of Perioperative Intravenous Lidocaine on Opioid Consumption and Pain After Laparoscopic Totally Extraperitoneal Inguinal Hernioplasty

Phase 4 Completed 64 enrolled B.P. Koirala Institute of Health Sciences

RandomizedParallel-groupTriple-blindTreatment

Summary

The primary objectives of this study is to access the effect of perioperative lidocaine infusion on total morphine requirement during the first 24 h postoperatively in patients who underwent laparoscopic totally extraperitoneal inguinal hernioplasty.

Timeline

Start: 2015-12
Primary completion: 2017-03
Completion: 2017-03

Outcome

Met primary endpoint

paper 0 (0-1) mg in the lidocaine group and 4 [1-8] mg in the saline group (p < 0.001). PMID 32493276 ↗

Publications

Ghimire A, Subedi A, Bhattarai B, Sah BP. The effect of intraoperative lidocaine infusion on opioid consumption and pain after totally extraperitoneal laparoscopic inguinal hernioplasty: a randomized controlled trial. BMC Anesthesiol. 2020 Jun 3;20(1):137. doi: 10.1186/s12871-020-01054-2.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Lidocaine	Other / unclassified	2 mg/kg	Intravenous

Indications

No indication recorded.