drugset / Trial / NCT02602314

Sustained Treatment-free Remission in BCR-ABL+ Chronic Myeloid Leukemia

NCT02602314

Phase 4 Unknown 450 enrolled GIMEMA Foundation
RandomizedParallel-groupOpen-labelTreatment

Summary

The study will investigate in newly diagnosed CP-CML patients the efficacy of NIL frontline therapy vs IM followed by switch to NIL in the case of absence of optimal response as defined by the ELN criteria.

Timeline

Start
2016-11-11
Primary completion
2023-02
Completion
2024-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Imatinib Small molecule 400 mg
Subject Nilotinib Small molecule 300 mg