drugset / Trial / NCT02609815
Initial Combination of Gemigliptin and Metformin on Microbiota Change
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to investigate gut microbiota change and glucose lowering effect of initial combination therapy of gemigliptin and metformin compared to glimepiride and metformin in obese patients with type 2 diabetes.
Timeline
- Start
- 2015-11-01
- Primary completion
- 2021-03-15
- Completion
- 2021-03-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Gemigliptin | Small molecule | 50 mg | — |
| Comparator | Glimepiride | Small molecule | 1 mg | — |
| Subject | Metformin | Small molecule | 500 mg | — |
| Subject | Metformin | Small molecule | 1000 mg | — |