drugset / Trial / NCT02613221
A Phase I/II Study for the Safety and Efficacy of Panitumumab in Combination With TAS-102 for Patients With Colorectal Cancer
NaSingle-groupOpen-labelTreatment
Summary
The purpose of this study is to evaluate the combination of panitumumab and Triflridine/Tipiracil (FTD/TPI; TAS-102) in patients with RAS wild-type metastatic colorectal cancer (CRC) refractory to standard chemotherapy (oxaliplatin, fluoropyrimidines, irinotecan and angiogenesis inhibitors).
Timeline
- Start
- 2015-12-07
- Primary completion
- 2017-10-06
- Completion
- 2018-03-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Panitumumab | Monoclonal antibody | 6 mg/kg | — |
| Subject | TAS-102 | Small molecule | 35 mg/m2 | Oral |