drugset / Trial / NCT02614404
Effect of Imatinib on Suppression of Malaria Parasites in Patients With Uncomplicated Plasmodium Falciparum Malaria
Phase 1
Completed
15 enrolled
HuLow
Hue University · collabPurdue University · collabUniversity of Turin, Italy · collabUniversità degli Studi di Sassari · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to determine the efficacy and safety of imatinib in combination with dihydroartemisinin plus piperaquine in the treatment uncomplicated P. falciparum malaria in adult male patients.
Timeline
- Start
- 2015-11
- Primary completion
- 2016-12-02
- Completion
- 2017-02-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Imatinib | Small molecule | 400 mg | — |
| Background | ARTENIMOL | Small molecule | 40 mg | — |
| Background | piperaquine | Small molecule | 320 mg | — |