drugset / Trial / NCT02616146
Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring and Levonorgestrel-Ethinyl Estradiol Combined Oral Contraceptive in Adult Women at Risk for Pregnancy (MK-8342B-062)
RandomizedParallel-groupOpen-labelPrevention
Summary
The purpose of this study is to assess the contraceptive efficacy of the etonogestrel + 17β-estradiol (ENG-E2) vaginal ring in women between 18 and 35 years of age based on the number of in-treatment pregnancies as expressed by the Pearl Index (PI). The study will also assess the safety and tolerability of ENG-E2 vaginal ring. The levonorgestrel-ethinyl estradiol (LNG-EE) 150/30 μg combined oral contraceptive (COC) will be used as the active comparator.
Timeline
- Start
- 2015-12-01
- Primary completion
- 2016-10-06
- Completion
- 2016-10-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Estradiol | Other / unclassified | 300 ug | Other |
| Subject | Etonogestrel | Unknown | 125 ug | Other |
| Comparator | Levonorgestrel | Small molecule | 150 ug | Oral |
| Comparator | ethinyl estradiol | Small molecule | 30 ug | Oral |
Indications
No indication recorded.