drugset / Trial / NCT02617810
A Study to Assess the Effect of Multiple-Dose Administration of JNJ-42847922 on Midazolam and Warfarin in Healthy Participants
NaSingle-groupOpen-labelTreatment
Summary
The purpose of this study is to evaluate effect of multiple-dose administration of JNJ-42847922 on the single-dose pharmacokinetics of oral midazolam and single-dose pharmacokinetics and pharmacodynamics of (R)- and (S)-warfarin after oral administration of racemic warfarin.
Timeline
- Start
- 2015-11
- Primary completion
- 2016-02
- Completion
- 2016-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Midazolam | Small molecule | 4 mg | Oral |
| Subject | Seltorexant | Small molecule | 20 mg | Oral |
| Subject | Warfarin | Small molecule | 25 mg | Oral |
Indications
No indication recorded.