drugset / Trial / NCT02620800

Study of 5-fluorouracil (5-FU), Nab®1-paclitaxel, Bevacizumab, Leucovorin, and Oxaliplatin in Patients With Metastatic Pancreatic Cancer

NCT02620800

Phase 1 Completed 12 enrolled Celgene Corporation
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to learn about the safety and potential benefit of metronomic 5-fluorouracil in combination with nab®1-paclitaxel, bevacizumab, leucovorin, and oxaliplatin in treating patients with metastatic pancreatic adenocarcinoma.

Timeline

Start
2016-01-18
Primary completion
2018-10-29
Completion
2018-10-29

Drugs

EvaluationDrugModalityDoseRoute
Subject Bevacizumab Monoclonal antibody 5 mg/kg Intravenous
Subject Leucovorin Small molecule 20 mg/m2 Intravenous
Subject Oxaliplatin Small molecule 40 mg/m2 Intravenous
Subject Paclitaxel Small molecule 75 mg/m2 Intravenous
Subject fluorouracil Small molecule 180 mg/m2 Intravenous