drugset / Trial / NCT02623569
To Assess the Anti-anginal Safety and Efficacy of Ivabradine in Subjects With Stable,Symptomatic Chronic Angina
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Arms Assigned Interventions Experimental: Ivabradine Ivabradine 5 mg twice a day for first 4 weeks and 7.5mg twice a day when positive ETT and HR\>60times/min or negative ETT and HR\>80times/min of subjects. Active Comparator: Atenolol Atenolol 12.5 mg twice a day for first 4 weeks and 25mg twice a day when positive ETT and heard rate\>60times/min or negative ETT and HR \>80times/min of subjects.
Timeline
- Start
- 2014-10
- Primary completion
- 2017-06
- Completion
- 2017-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Atenolol | Other / unclassified | 12.5 mg | — |
| Comparator | Atenolol | Other / unclassified | 25 mg | — |
| Subject | Ivabradine | Small molecule | 5 mg | — |
| Subject | Ivabradine | Small molecule | 7.5 mg | — |