drugset / Trial / NCT02623569

To Assess the Anti-anginal Safety and Efficacy of Ivabradine in Subjects With Stable,Symptomatic Chronic Angina

NCT02623569

Phase 2 Unknown 336 enrolled Xintong Pharmacy Company
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Arms Assigned Interventions Experimental: Ivabradine Ivabradine 5 mg twice a day for first 4 weeks and 7.5mg twice a day when positive ETT and HR\>60times/min or negative ETT and HR\>80times/min of subjects. Active Comparator: Atenolol Atenolol 12.5 mg twice a day for first 4 weeks and 25mg twice a day when positive ETT and heard rate\>60times/min or negative ETT and HR \>80times/min of subjects.

Timeline

Start
2014-10
Primary completion
2017-06
Completion
2017-06

Drugs

EvaluationDrugModalityDoseRoute
Comparator Atenolol Other / unclassified 12.5 mg
Comparator Atenolol Other / unclassified 25 mg
Subject Ivabradine Small molecule 5 mg
Subject Ivabradine Small molecule 7.5 mg