drugset / Trial / NCT02625753
Codeine Plus Paracetamol Versus Placebo for PRK Post-operative Pain
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Compare the use of codeine/paracetamol against placebo for pain control after cornea photorefractive keratectomy (PRK).
Timeline
- Start
- 2014-11
- Primary completion
- 2015-06
- Completion
- 2015-10
Publications
- Pereira VBP, Torriceli AAM, Garcia R, Bechara SJ, Alves MR. Codeine plus acetaminophen improve sleep quality, daily activity level, and food intake in the early postoperative period after photorefractive keratectomy: a secondary analysis. Arq Bras Oftalmol. 2021 Jan-Feb;84(1):45-50. doi: 10.5935/0004-2749.20210008.
- Pereira VBP, Garcia R, Torricelli AAM, Mukai A, Bechara SJ. Codeine Plus Acetaminophen for Pain After Photorefractive Keratectomy: A Randomized, Double-Blind, Placebo-Controlled Add-On Trial. Cornea. 2017 Oct;36(10):1206-1212. doi: 10.1097/ICO.0000000000001328.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Acetaminophen | Small molecule | 500 mg | Oral |
| Comparator | Codeine | Small molecule | 50 mg | Oral |