drugset / Trial / NCT02632565
Intra-Articular 0.5 % Lidocaine Injection for Osteoarthritis
RandomizedParallel-groupQuadruple-blindTreatment
Summary
In this study, investigators compared the efficacy of intra-articular 0.5% lidocaine and saline injection on pain, stiffness and physical function in patients with osteoarthritis.
Timeline
- Start
- 2009-12
- Primary completion
- 2015-03
- Completion
- 2015-08
Publications
- Background Elhakim M, Nafie M, Eid A, Hassin M. Combination of intra-articular tenoxicam, lidocaine, and pethidine for outpatient knee arthroscopy. Acta Anaesthesiol Scand. 1999 Sep;43(8):803-8. doi: 10.1034/j.1399-6576.1999.430804.x.
- Background Pietruck C, Grond S, Xie GX, Palmer PP. Local anesthetics differentially inhibit sympathetic neuron-mediated and C fiber-mediated synovial neurogenic plasma extravasation. Anesth Analg. 2003 May;96(5):1397-1402. doi: 10.1213/01.ANE.0000060454.34258.D3.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Lidocaine | Other / unclassified | 0.5 % | Other |
| Comparator | Lidocaine | Other / unclassified | 7 ml | Other |