Nutrition Supplementation in Hospitalized Patients

Summary

Patients with severe malnutrition risk are 7.4 times more likely to die in hospital than well-nourished patients, and carry a 30-day readmission rate of \>46%. Although malnutrition is common and is associated with extremely poor outcomes, it is neglected and undertreated. This is a randomized controlled pilot trial to rapidly identify at-risk hospitalized medical patients, and then provide nutritional supplementation in hospital and after discharge for 28 days. In select at-risk patients, 5 days of nutrition delivered through a peripheral vein will be used in addition to oral nutritional supplementation.

Timeline

Start

2016-03

Primary completion

2018-02

Completion

2018-02

Publications

• Mrkobrada M, Patel A, Chakroborty A, Handsor S, Armstrong D, Rahman A. NutriSup-PPN: A pilot randomized control trial of oral nutritional supplementation (ONS) and peripheral parenteral nutrition (PPN) in canadian, malnourished, hospitalized patients. Clin Nutr ESPEN. 2023 Feb;53:107-112. doi: 10.1016/j.clnesp.2022.04.008. Epub 2022 Apr 23.

Drugs

Indications