drugset / Trial / NCT02636803
Study of the Efficacy of Oxfendazole Compared to Albendazole in the Treatment of Trichuris Trichiura Infection in Adults
Phase 2
Withdrawn
Johns Hopkins Bloomberg School of Public Health
Universidad Peruana Cayetano Heredia · collab
RandomizedFactorialSingle-blindTreatment
Summary
The aim of this study is to provide data on the efficacy of oxfendazole against Trichuris trichiura at different doses in comparison to the standard single 400 mg dose of albendazole. In addition, the study will provide data on oxfendazole efficacy against other common nematodes encountered in man (Enterobius vermicularis, Ascaris lumbricoides, Ancylostoma duodenalis, Necator americanus).
Timeline
- Start
- 2019-11
- Primary completion
- 2020-08
- Completion
- 2021-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Albendazole | Small molecule | 400 mg | Oral |
| Subject | Oxfendazole | Small molecule | 6 mg/kg | Oral |
| Subject | Oxfendazole | Small molecule | 30 mg/kg | Oral |