drugset
drugset / Trial / NCT02637726

Bispectral Index Under Propofol Anesthesia in Children : a Study Between TIVA and TCI

NCT02637726 ↗

Completed 66 enrolled Pr Isabelle CONSTANT
RandomizedParallel-groupDouble-blindTreatment

Summary

In children, only a few studies have compared different modes of propofol infusion during a total intravenous anesthesia (TIVA) with propofol and remifentanil. The aim of this study is to compare Bispectral Index (BIS) profiles (percentage of time spent at adequate BIS values) between four modes of propofol infusion: titration of the infusion rate on clinical signs (TIVA0), titration of the infusion rate on the BIS (TIVABIS), target controlled infusion (TCI) guided by the BIS either with the Kataria model (TCI KBIS) or the Schnider model (TCI SBIS). Methods: Children will be prospectively randomized into the 4 groups. In the TIVA0 group the anesthesiologist is blinded to the BIS. In each group, the percentage of time with adequate BIS values (45-55), the bias and imprecision will be calculated.

Timeline

Start
2006-02
Primary completion
2007-03
Completion
2007-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Propofol Small molecule — —
Background Remifentanil Small molecule — —

Indications

No indication recorded.