drugset / Trial / NCT02641457

Intravitreal Aflibercept or Ranibizumab for Rubeosis Iridis

NCT02641457

Phase 3 Completed 2 enrolled Instituto de Olhos de Goiania
NaSingle-groupOpen-labelTreatment

Summary

Aflibercept (Eylea®) and ranibizumab (Lucentis®) are an anti-VEGF, but there are differences between the two drugs. To determine and compare whether intraocular aflibercept and ranibizumab decreases rubeosis iridis (RI) in patients with neovascular glaucoma (NVG).

Timeline

Start
2014-03
Primary completion
2015-03
Completion
2015-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Aflibercept Protein / enzyme biologic 2 mg Intravitreal
Subject Ranibizumab Monoclonal antibody 1.25 mg Intravitreal