drugset / Trial / NCT02642523
Natriuretic Peptides and Metabolic Risk in Obesity
Non-randomizedCrossoverOpen-labelOther
Summary
The investigators are examining: 1. the relationships of insulin levels and natriuretic peptide hormone levels, and 2. the effects of administering an infusion of natriuretic peptide hormone on the breakdown of fat in healthy lean and otherwise healthy obese individuals.
Timeline
- Start
- —
- Primary completion
- 2017-02
- Completion
- 2017-02
Outcome
Outcome not reported
Stopped: “Preliminary data run on rat samples showed that this study question and design would not produce conclusive results. The PI decided not to carry out the study.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Insulin | Protein / enzyme biologic | — | Intravenous |
| Subject | Nesiritide | Protein / enzyme biologic | 0.01 ug/kg | Intravenous |