drugset / Trial / NCT02645734
The Effect of Bevacizumab and Ziv-aflibercept in Diabetic Macular Edema
RandomizedParallel-groupDouble-blindTreatment
Summary
In this double clinical trial 132 patient with the history of DME (Diabetic Macular Edema) to receive intravitreous bevacizumab at a dose of 1.25mg (44 patient) , ziv-aflibercept at dose of 1.25 mg (44 patient) , ziv-aflibercept at dose of 2.5 mg (44 patient) . The study drugs were administered as often as every 4 weeks for 3 months.monitoring of best-corrected visual acuity, CST ( Central Subfield Thickness) by OCT (Optical coherence tomography) was done from base line ,4 weeks, 8weeks after injection.
Timeline
- Start
- —
- Primary completion
- 2016-02
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Aflibercept | Protein / enzyme biologic | 1.25 mg | Intravitreal |
| Comparator | Aflibercept | Protein / enzyme biologic | 2.5 mg | Intravitreal |
| Comparator | Bevacizumab | Monoclonal antibody | 1.25 mg | Intravitreal |