drugset / Trial / NCT02646670
Efficacy of Ranibizumab Therapy With Aflibercept in Patients With Diabetic Macular Edema
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study in to compare the efficacy of treatment of diabetic macular edema (DME) using Ranibizumab (Lucenti®), Aflibercept (Eylea®) and Aflibercept (Eylea®) plus Ranibizumab (Lucentis®). It is a randomized clinical trial that will evaluate the efficacy of the combination of two substances currently used in the treatment of DME. Will be allocated in different four groups randomly pacients who receive treatment with intravitreal injections of ranibizumab, aflibercept or a combination of aflibercept and ranibizumab.
Timeline
- Start
- 2015-07
- Primary completion
- 2015-10
- Completion
- 2015-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Aflibercept | Protein / enzyme biologic | 0.1 ml | Intravitreal |
| Comparator | Ranibizumab | Monoclonal antibody | 0.1 ml | Intravitreal |