drugset / Trial / NCT02646670

Efficacy of Ranibizumab Therapy With Aflibercept in Patients With Diabetic Macular Edema

NCT02646670

Phase 4 Completed 20 enrolled Instituto de Olhos de Goiania
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study in to compare the efficacy of treatment of diabetic macular edema (DME) using Ranibizumab (Lucenti®), Aflibercept (Eylea®) and Aflibercept (Eylea®) plus Ranibizumab (Lucentis®). It is a randomized clinical trial that will evaluate the efficacy of the combination of two substances currently used in the treatment of DME. Will be allocated in different four groups randomly pacients who receive treatment with intravitreal injections of ranibizumab, aflibercept or a combination of aflibercept and ranibizumab.

Timeline

Start
2015-07
Primary completion
2015-10
Completion
2015-11

Drugs

EvaluationDrugModalityDoseRoute
Comparator Aflibercept Protein / enzyme biologic 0.1 ml Intravitreal
Comparator Ranibizumab Monoclonal antibody 0.1 ml Intravitreal

Indications