drugset / Trial / NCT02647788

Acetaminophen/Codeine vs Acetaminophen/Ibuprofen for Pain Control and Patient Satisfaction After Hand Surgery

NCT02647788

Phase 4 Completed 144 enrolled University of Pennsylvania
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this research study is to find out if taking Acetaminophen with Ibuprofen (e.g. Tylenol + Advil), a non-opioid regimen, provides the same type of pain relief after hand surgery compared to Acetaminophen and codeine (e.g. Tylenol 3), an opioid regimen.

Timeline

Start
2015-12
Primary completion
2018-01-19
Completion
2018-01-19

Drugs

EvaluationDrugModalityDoseRoute
Comparator Acetaminophen Small molecule 300 mg
Comparator Acetaminophen Small molecule 650 mg
Comparator Codeine Small molecule 30 mg
Comparator Ibuprofen Small molecule 400 mg

Indications