An Interventional Study for Patient With Cancer Pain to Evaluate the Efficacy and Safety of OxyNorm® Compared to Morphine Sulfate Through the IV Continuous Infusion.

Phase 4 Completed 66 enrolled Mundipharma Korea Ltd

RandomizedParallel-groupOpen-labelSupportive care

Summary

The purpose of this study is to compare of difference in NRS scores from baseline to the completion of treatment (5 days) in patients with administration of morphine sulfate versus oxycodone hydrochloride.

Timeline

Start: 2015-11
Primary completion: 2016-07
Completion: 2016-07

Outcome

Missed primary endpoint

paper While this reduction was similar between groups (3.5 ± 2.2 versus 3.1 ± 1.8, P value = 0.562) PMID 29670416 ↗

Publications

Lee KH, Kang JH, Oh HS, Choi MK, Shim BY, Eum YJ, Park HJ, Kang JH. Intravenous Oxycodone versus Intravenous Morphine in Cancer Pain: A Randomized, Open-Label, Parallel-Group, Active-Control Study. Pain Res Manag. 2017;2017:9741729. doi: 10.1155/2017/9741729. Epub 2017 Oct 31.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Morphine	Other / unclassified	—	Intravenous
Subject	Oxycodone	Other / unclassified	—	Intravenous

Indications

No indication recorded.